Inflammation Control Compounds - ICC

ICC (Inflammation control compounds)

60 x 500mg Capsules

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• Reduces various inflammatory mediators

• Including: interleukin-6 (IL-6), IL-1 beta, TNF-alpha, prostaglandin E2 and leukotrienes

Indications

• Chronic Inflammation

• Rheumatoid & osteoarthritis

• Ulcerative colitis

• Crohn's disease

• Eczema

• SLE

• Cancer Protocols

• Lung cancer

• Breast Cancer

• Colorectal Cancer

• Inflammation induced angiogenesis

Ingredients:

Gentiana macrophylla

Folium Urtica dioica 

Folium Ocimum sanctum 
(contains extract 2.5% Ursolic acid) (Lou Le)

Radix Zingiber officinale 
(contains extract 20% gingerols) (ShengJjiang)

Gum Boswellia serrata (30% AKBA) (Ru Xiang)

Camiella sinensis (Extract EGCG 40%) (Lu Cha)

Citrus reticulata 

Perilla frutsecens

Other Ingredients: Vegetable cellulose (hypromellose); Vegetable Stearic Acid; Microcrystalline Cellulose and Vegetable Magnesium Stearate.

Does Not Contain: Wheat, gluten, soy, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts

Caution: Rare side-effects of Boswellia include diarrhoea, skin rash, acid reflux and nausea and maybe contraindicated in those with pre-existing gastritis or gastrooesophageal reflux disease (GERD). Studies suggest Boswellia moderates 5-lipoxygenase and therefore may interact with leukotriene inhibitors.

Warning: Not to be taken by pregnant or lactating women 

Suggested Use: 2 capsules twice daily on empty stomach. For treatment of systemic inflammation alternate with Berberine Complexevery 6 weeks (2 caps 2 times daily on empty stomach)

Key Ingredients

Folium Urtica dioica (Stinging Nettle Leaf)

References

1. Klingelhoefer S et al. Antirheumatic effect of IDS23, a stinging nettle leaf extract, on in vitro expression of T helper cytokines. J Rheumatol 1999, 26:2517-22. 

2. Broer J, Behnke B. Immunosuppressant effect of IDS30, a stinging nettle leaf extract, on myeloid dendritic cells in vitro. J Rheumatol 2002, 29:659-66. 

3. Konrad A et al,. Ameliorative effect of IDS30, a stinging nettle leaf extract, on chronic colitis. Int J Colorectal Dis 2005, 20:9-17. 

Folium Ocimum sanctum (contains extract 2.5% Ursolic acid) (Lou Le)

References

1. Archana R, Namasivayam A. Effect of Ocimum sanctum on noise induced changes in neutrophil functions. J Ethnopharmacol 2000, 73:81-85. 

2. Sembulingam K et al,. Effects of Ocimum sanctum Linn on noise induced changes in plasma corticosterone level. Indian J Physiol Pharmacol 1997, 41:139-43. 

3. Manev H et al,. Putative role of neuronal 5-lipoxygenase in an aging brain. FASEB J 2000, 14:1464-69.

Radix Zingiber officinale (containing gingerols) (Sheng Jiang) 

References

1. Srivastava K, Mustafa T. Ginger (Zingiber officinale) and rheumatic disorders. Med Hypoth 1989, 29:25-28. 

2. Broer J, Behnke B. Immunosuppressant effect of IDS30, a stinging nettle leaf extract, on myeloid dendritic cells in vitro. J Rheumatol 2002, 29:659-66.

Gum Boswellia serrata (Ru Xiang)

References

1. Sailer E et al,. Acetyl-11-keto- [beta]-boswellic acid (AKBA): structure requirements for binding and 5-lipoxygenase inhibiting activity. Br J Pharmacol 1996, 117:615-18. 

2. Uz T et al,. Aging-associated up-regulation of neuronal 5-lipoxygenase expression: putative role in neuronal vulnerability. FASEB J 1998, 12:439-49. 

3. Steele V et al,. Lipoxygenase inhibitors as potential cancer chemopreventives. Cancer Epidemiol Biomarkers Prev 1999, 8:467-83. 

Green Tea (Lu Cha)

References

1. Dona M et al. Neutrophil restraint by green tea: inhibition of inflammation, associated angiogenesis, and pulmonary fibrosis. J Immunol 2003, 170:4335-41.