ORGANIC ACIDS AND N.A.D+

The Organic Acids and NAD+ profile is a comprehensive look at cellular metabolism, energy production, detoxification and neurological function. These tests complement each other, and are suitable for investigating fatigue, cognitive issues, mitochondrial dysfunction, inflammation, and/or ageing-related concerns.

The Organic Acids test measures 50+ metabolic by products assisting the Practitioner in understanding key pathways in:

•  • Mitochondrial function (energy production: citric acid cycle)
•  • Nutrient deficiencies (B-vitamins, antioxidants, amino acids)
•  • Detoxification (glutathione status, Phase I/II liver function)
•  • Neurotransmitter metabolism (dopamine, serotonin markers)
•  • Oxidative stress & inflammation
•  • Yeast & bacterial overgrowth
•  • Fatty acid and oxalate metabolism

NAD+ is essential for ATP production, DNA repair, neurotransmitter metabolism, and immune modulation. This test measures the following key markers:

•  • NAD+ = nicotinamide Adenine Dinucleotide, Oxidised form
•  • NADH = Nicotinamide Adenine Dinucleotide, Reduced form
•  • NADP+ = Nicotinamide Adenine Dinucleotide Phosphate, Oxidised form
•  • NADPH = Nicotinamide Adenine Dinucleotide Phosphate, Reduced form

Test details

• Test code: 1025
• Category: Mental Health
• Kit requirements: Spot Urine & Blood Spot
• Collection method: Blood Spot and Spot Urine
• Test method: Liquid Chromatography–Tandem Mass Spectrometry with Triple Quadrupole (LCMS/MS/MS)
• Turnaround time: 14 Business Days

What is measured

• 2-Methylhippuric Acid
• 3-OH-Proprionic Acid
• 4-Cresol
• 5-Hydroxyindoleacetic Acid (5HIAA)
• 8-OH-deoxyguanosine
• a-Keto-b-Methylvaleric Acid
• a-Ketoglutaric Acid
• a-Ketoisocaproic Acid
• a-Ketoisovaleric Acid
• a-OH-Butyric Acid
• Adipic Acid
• Arabinitol
• Ascorbic Acid (Vit C)
• B-Complex Vitamins & Amino Acid
• b-OH-b-Methylglutaric Acid
• b-OH-Butyric Acid
• Benzoate (OA)
• beta-Hydroxyisovaleric Acid
• Biotin (Vit H)
• Carbohydrate Metabolism
• cis-Aconitic Acid
• Citramalic Acid
• Citric Acid
• Citric acid cycle metabolites
• Clostridium species
• CoEnzyme-Q10 (CoQ10)
• Cortisol (OA)
• Creatinine
• Detoxification Indicators
• Dihydroxyphenylpropionic Acid
• Ethylmalonic Acid
• Fumaric Acid
• Glucaric Acid
• Glucose (OA)
• Glutaric Acid (Vit B2)
• Glyceric Acid
• Glycolic Acid
• Hippurate (OA)
• Homovanillic Acid (HVA)
• Indoleacetic Acid
• Isocitric Acid
• Ketone/fatty acid metabolites
• Kynurenic Acid
• L. acidophilus/General Bacteria
• Lactic Acid
• Malic Acid
• Methyl-Succinic Acid
• METHYLATION COFACTORS
• N-Acetylcysteine (NAC)
• NAD+ (Nicotinamide Adenine Dinucleotide, Oxidised form)
• NADH (Nicotinamide Adenine Dinucleotide, Reduced form)
• NADP+ (Nicotinamide Adenine Dinucleotide Phosphate, Oxidised form)
• NADPH (Nicotinamide Adenine Dinucleotide Phosphate, Reduced form)
• NEUROTRANSMITTER METABOLISM
• Organic acids
• Orotic Acid
• Oxalic Acid
• Oxidative Damage/Antioxidant Markers
• p-HydroxyPhenylacetate
• Pantothenic Acid (Vit B5)
• ParaHydroxyBenzoate
• ParaHydroxyphenyllactate
• Phenylacetate
• Phenylpropionate
• Picolinic Acid
• Pimelic Acid
• Pyridoxic Acid (Vit B6)
• Pyroglutamic Acid
• Pyruvic Acid
• Quinolinic Acid (OA)
• Suberic Acid
• Succinic Acid
• Tartaric Acid
• Tricarballylate
• Vanillylmandelic Acid (VMA)
• Xanthurenic Acid
• YEAST/FUNGAL DYSBIOSIS MARKERS

Common clinical applications

• Cardiovascular Health
• Detoxification
• Autoimmune and Immune System
  • Immune dysfunction
• Mental and Emotional Health
  • Mental health
• Metabolic Function
• Nutrient Deficiency

This test should be ordered and interpreted with guidance from a qualified healthcare practitioner.

Important: Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.