GutIQ – GI Metagenomic Mapping

Shotgun Metagenomics Microbiomix

The GutIQ (formerly Microbiomix) test utilises metagenomic sequencing (shotgun), a powerful technique for analysing the genetic material of entire microbial communities present in a given stool sample. The term “shotgun” refers to the random and unbiased sequencing of all the genetic material in the sample, including DNA from bacteria, viruses, fungi, and other microorganisms. Covering 28,000+ microbial species, this comprehensive analysis provides a more detailed picture compared to targeted approaches that focus on specific genes or organisms.

Since the sequencing is unbiased, it can reveal the presence of previously unknown or unculturable microorganisms to uncover the full diversity of the microbiome. Through a simple stool sample, this panel provides detailed information on the microbiome, as well as biochemical markers relating to digestion, inflammation, intestinal permeability, and more.

The test report also comes with a dynamic GutIQ Species Explorer tool that allows you to dive into every organism detected through the metagenomic sequencing technology. Color coding and built-in filters allow you to easily navigate each organism detected for health and disease risk, phylum distribution, Deviation from normal ranges, and more.

Test details

• Test code: 2212
• Category: Microbiome Health
• Kit requirements: Stool Test Kit
• Collection method: CI05.53.01
• Test method: Metagenomic Next Generation Sequencing (mNGS) Quantitative PCR (qPCR), Polymerase Chain Reaction (PCR) Chemiluminescence Immunoassay (CLIA) Enzyme-Linked Immunosorbent Assay (ELISA) Fluorescence Enzyme Immunoassay (FEIA) Gas Chromatography-MS (GC/MS)
• Turnaround time: 7-10 Business Days

What is measured

• Beta Glucuronidase
• Faecal Markers
  • Calprotectin
  • Pancreatic Elastase
• Identification of 28,000+ microbial species
• pH
• SCFA- butyrate, acetate, propionate, valerate
• Secretory IgA
• Steatocrit
• Transglutaminase Immunoglobulin A (IgA)
• Zonulin

Common clinical applications

• Gastrointestinal and Digestive Health
  • Abdominal pain
  • Bloating, gas and distention
  • Constipation
• Other Health Conditions
  • Food intolerances
  • IBS/IBD
  • Metabolic disorders
• Nutritional and Dietary Symptoms
  • Malnutrition/ malabsorption/ maldigestion

Resources

• Sample Report

This test should be ordered and interpreted with guidance from a qualified healthcare practitioner.

Important: Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.