NutriPATH
Growth Hormone
Growth Hormone
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Growth hormone stimulates nearly every tissue in the body and can be generally described as having an anabolic function. An adult-onset growth hormone deficiency is common and can present as central obesity, diminished memory, impaired sleep, low libido, osteoporosis and cardiovascular disease. By diagnosing and treating the decline of GH age-related these changes in body composition, mood and overall quality of life can be ameliorated. Numerous studies using GH therapy in the ageing population has shown improvements in lean muscle mass, total body fat, bone and cardiovascular parameters.
Growth hormone (GH) is a peptide hormone secreted from the anterior pituitary gland. Its secretion is regulated by two hypothalamic hormones; somatostatin which inhibits GH secretion, and growth hormone releasing hormone (GHRH) which stimulates it. The secretion of GH occurs in a pulsatile fashion with the main peak occurring at 12-1am in healthy adults.
The symptoms of a growth hormone deficiency depend on the age of onset of this hormone imbalance. Whilst children typically present with short stature, adults have alterations in muscle, fat, bone and psychological parameters. Adult-onset growth hormone deficiency is common. At the age of 60, most individuals have only 25% of the GH they did at age 20. Furthermore, about 50% of 80 year olds have no detectable growth hormone. Therefore it is not surprising that the ageing population experience the symptoms associated with a growth hormone deficiency such as central obesity, diminished memory, impaired sleep, low libido, osteoporosis and cardiovascular disease.
References:Kužma M, Jackuliak P, Killinger Z, Vaňuga P, Payer J. Problematika sekundárnej osteoporózy pri deficite rastového hormónu v dospelosti [Issues related to secondary osteoporosis associated with growth hormone deficiency in adulthood]. Vnitr Lek. 2017;63(10):658‐661
Johannsson G, Svensson J, Bengtsson BA. Growth hormone and ageing. Growth Horm IGF Res. 2000;10 Suppl B:S25-S30. doi:10.1016/s1096-6374(00)80006-4
Test details
- Test code: 1118
- Category: Hormone Health
- Kit requirements: SST Serum (Fasting)
- Collection method: CI05.15.01
- Test method: Automated chemistry (Roche Diagnostics)
- Turnaround time: 5 Business Days
What is measured
- Arsenic
- Bromine
- Cadmium
- Iodine
- Lithium
- Mercury
- Selenium
Common clinical applications
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Autoimmune and Immune System- Autoimmune diseases (eg. multiple sclerosis)
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Cardiovascular Health- Cardiovascular Disease
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Other Health Conditions- Chronic bone/muscle/joint pain
- Depression & mood disorders
- Diabetes type I & II
- Osteoporosis
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Nutritional and Dietary Symptoms- Chronic Fatigue
Resources
This test should be ordered and interpreted with guidance from a qualified healthcare practitioner.
Important: Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.
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