Cytokine Panel

Cytokines are chemical messengers that primarily signal the immune system, but also play a role as neuromodulators. They can be defined as either pro-inflammatory or anti-inflammatory. Cytokine imbalances may be involved in autoimmune disorders, atopic conditions as well as neuropsychiatric disorders.

Cytokines are signaling proteins and glycoproteins that mediate and regular immunity, inflammation and hematopoiesis.  They are also involved in cell growth and differentiation, cell death, angiogenesis, normal development and neuromodulations.

Cytokines are critical to the functional both innate (cell-mediated) and adaptive (antigen specific/humoral) immune systems.  They are known as either pro-inflammatory or anti-inflammatory.  Pro-inflammatory cytokines include interferon-gamma (INFγ), interleukin-2 (IL2) and interleukin-12 (IL12); whereas interleukin-4 (IL4) and interleukin-5 (IL5) are anti-inflammatory.

Generally pro-inflammatory cytokines are secreted from T-helper 1 (Th1) cells and anti-inflammatory cytokines are secreted from T-helper 2 (Th2) cells.  Under normal circumstances the Th1 and Th2 systems should be in balance.

Test details

• Test code: 4004
• Category: Environmental
• Kit requirements: Blood Spot or SST
• Collection method: CI05.15.01
• Test method: EIA (Enzyme immunoassay)
• Turnaround time: 12-15 Business Days

What is measured

• GM-CSF
• IFN Gamma
• IL-10
• IL-12
• IL-13
• IL-17
• IL-1A
• IL-2
• IL-4
• IL-5
• IL-6
• IL-7
• IL-8
• TNFa
• TNFB

Common clinical applications

• Respiratory Health
  • Asthma
• Mental and Emotional Health
  • Depression
• Skin and Dermatological Health
  • Eczema
• Other Health Conditions
  • Food intolerances
  • Inflammatory Bowel Disease
• Autoimmune and Immune System
  • Hashimotos Thyroiditis
• Reproductive Health
  • Recurrent miscarriages
• Muscle and Joint Health
  • Rheumatoid arthritis

Resources

• Patient Brochure
• Sample Report

This test should be ordered and interpreted with guidance from a qualified healthcare practitioner.

Important: Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.