NutriPATH
Cortisol Profile
Cortisol Profile
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The Adrenocortex hormone profile is a non-invasive saliva test that serves as a reliable marker of stress response and a critical tool for revealing adrenal imbalances. Lifestyle, physical and psychological stresses put constant demands on the adrenal glands. If they become depleted adrenal fatigue or insufficiency may be experienced.
Each person has two adrenal glands both located on top of each of the body’s two kidneys. These glands are important to the body’s endocrine (hormonal) system. Adrenal fatigue is a very common condition in today’s society through the physical and physiological demands we put on our adrenal glands. Each gland is composed of two distinct zones, the large outer cortex and the inner medulla.
Salivary cortisol testing is the most accurate and powerful non-invasive salivary hormone test that evaluates bioactive levels of the body’s important stress hormone cortisol. This hormone test (stress test) serves as a critical tool for uncovering biochemical imbalances underlying anxiety, depression, chronic fatigue syndrome, obesity, dysglycemia, and a host of other clinical conditions that may affect our day to day lives. This hormone test examines 4 saliva samples over a 12-hour period for levels of cortisol 8am, 12pm, 4pm, and 8pm. The cortisol profile is particularly useful for patients with fatigue.
References:Tsigos C, Chrousos GP. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. Journal of psychosomatic research. 2002;53(4):865-871.
Fries E, Dettenborn L, Kirschbaum C. The cortisol awakening response (CAR): facts and future directions. IntJPsychophysiol. 2009;72(1):67-73.
Clow A, Hucklebridge F, Stalder T, Evans P, Thorn L. The cortisol awakening response: more than a measure of HPA axis function. NeurosciBiobehavRev. 2010;35(1):97-103.
Hackett RA, Kivimäki M, Kumari M, Steptoe A. Diurnal Cortisol Patterns, Future Diabetes, and Impaired Glucose Metabolism in the Whitehall II Cohort Study. The Journal of Clinical Endocrinology & Metabolism. 2016;101(2):619-625.
Hammer F, Deutschbein T, Marx A, et al. High evening salivary cortisol is an independent predictor of increased mortality risk in patients with systolic heart failure. International journal of cardiology. 2016;203:69-73.M
Test details
- Test code: 1003
- Category: Hormone Health
- Kit requirements: 4 x 5ml Saliva
- Collection method: CI05.01.01
- Test method: LC-MS
- Turnaround time: 3-5 Business Days
What is measured
- Cortisol 12:00pm
- Cortisol 4:00pm
- Cortisol 6:00-8:00am
- Cortisol 8:00pm
Common clinical applications
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Mental and Emotional Health- Anxiety
- Depression
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Cardiovascular Health- Blood Pressure
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Other Health Conditions- Energy levels
- Fatigue, lethargy
- Headaches
- Irregular sleeping patterns
- Lack of stamina
- Mild depression
- Sexual dysfunction
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Autoimmune and Immune System- Impaired immune system
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Energy and Fatigue- Poor concentration, ‘brain fog’
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Nutritional and Dietary Symptoms- Salt cravings
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Endocrine and Hormonal Health- Thyroid dysfunction
Resources
This test should be ordered and interpreted with guidance from a qualified healthcare practitioner.
Important: Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.
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