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NutriPATH

Anti-Gliadin Antibodies

Anti-Gliadin Antibodies

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Gliadin is a protein found in gluten-containing grains like wheat, barley, and rye. Anti-gliadin antibodies are immune proteins produced response to the presence of gliadin in the body.

The anti-gliadin antibody test is useful for supporting the diagnosis of coeliac disease and non-celiac gluten sensitivity (2). When individuals with coeliac disease ingest gluten, their immune system mistakenly targets and damages the lining of the small intestine, leading to villous atrophy, mucosal inflammation, and systemic symptoms (2).

Through the detection of IgG and IgA anti-gliadin antibodies this panel can help confirm the need for affected individuals to follow a gluten-free diet to manage their condition and alleviate related health issues.

References:

1. Benson BC, Mulder CJ, Laczek JT. Anti-gliadin antibodies identify celiac patients overlooked by tissue transglutaminase antibodies. Hawai’i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health [Internet]. 2013;72(9 Suppl 4):14–7. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764583/

Test details

  • Test code: 3407
  • Category: Environmental
  • Kit requirements: SST Serum
  • Collection method: CI05.15.01
  • Test method: EIA (Enzyme immunoassay)
  • Turnaround time: 2 Business Days

What is measured

  • Deamidated gliadin antibodies IgG & IgA

Common clinical applications

  • Nutritional and Dietary Symptoms
    • Coeliac
    • Gluten sensitivity/ intolerance
  • Gastrointestinal and Digestive Health
    • Gastrointestinal issues
  • Other Health Conditions
    • Inflammation
  • Skin and Dermatological Health
    • Skin conditions

Resources

This test should be ordered and interpreted with guidance from a qualified healthcare practitioner.

Important: Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.

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