Anaemia Autoimmunity

Intrinsic Factor antibodies and Gastric Parietal Cell antibodies are autoantibodies linked to autoimmune conditions such as pernicious anaemia and autoimmune gastritis. Intrinsic Factor, produced by the cells in the stomach lining, is crucial for vitamin B12 absorption. When Intrinsic Factor antibodies mistakenly attack this protein, vitamin B12 absorption is impaired, potentially causing pernicious anaemia and neurological issues. Gastric Parietal Cell antibodies target the stomach’s parietal cells, which produce both intrinsic factor and gastric acid. Their presence indicates autoimmune gastritis, often leading to gastric mucosa atrophy and reduced production of intrinsic factor and hydrochloric acid. Both Intrinsic Factor and Gastric Parietal Cell antibodies are associated with vitamin B12 deficiency, making their detection vital for diagnosing and managing autoimmune stomach conditions. Identifying these antibodies can guide treatment strategies and help monitor disease progression, supporting better patient outcomes.

Test details

• Test code: 6114
• Category: Routine Pathology
• Kit requirements: SST Kit
• Collection method: CI05.15.01
• Turnaround time: 7 Business Days

Common clinical applications

• Abdominal pain and bloating
• Blurred or impaired vision
• Depression and irritability
• Other Health Conditions
  • Fatigue
• Inflamed and smooth tongue
• Memory loss and confusion
• Nutritional and Dietary Symptoms
  • Pernicious Anaemia
• Tingling or numbness in hands and feet

Resources

• Patient Brochure
• Sample Report

This test should be ordered and interpreted with guidance from a qualified healthcare practitioner.

Important: Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.