Affect D

Affect D is an anxiolytic and sedative and may be used for medium to severe depression, bi-polar disorders, acute insomnia, OCD and PTSD. Affect D combines Western therapeutic compounds with traditional Chinese herbs as well as a specific molecular extract from a famous pain herb. Affect D is an all-natural product, which has similar therapeutic effects of well-known pharmaceuticals to treat severe psychological conditions.

Ingredients

Affect D is a superior combination of botanicals and isolates. Psychopharmacologic indications include Post Traumatic Stress Disorder (PTSD) Obsessive Compulsive Disorder (OCD) and depression.

Ingredients
Cyanocobalamin
Levomefolate calcium
Methionine
Phenylalanine
Pyridoxal-5-Phosphate
Zinc succinate
Bupleurum falcatum
Curcuma longa
Cyperus rotundus
Dalbergiae odoriferae
Hypericum perforatum
Magnolia officinalis
Ziziphus jujuba var spinosa

Other Ingredients: Vegetable cellulose (hypromellose); Vegetable Stearic Acid; Microcrystalline Cellulose and Vegetable Magnesium Stearate.

Does not contain: Wheat, gluten, soy, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts

Actions & Indications

Affect-D 

Affect D is an anxiolytic and sedative and may be used for medium to severe depression, bi-polar disorders, acute insomnia, OCD and PTSD. Affect D combines Western therapeutic compounds with traditional Chinese herbs as well as a specific molecular extract from a famous pain herb. Affect D is an all-natural product, which has similar therapeutic effects of well-known pharmaceuticals to treat severe psychological conditions.

Actions

Relieves medium to severe depression

Balances mood

Anxiolytic

Sedative

Regulates sleeping patterns and improves daytime alertness

Treats physical and mental fatigue

Assists with optimum cognitive functioning

Stimulates neuronal regeneration in the brain

Increases 5-HTP

Indications

Medium to severe depression

Bi-polar disorders

Acute insomnia

OCD

PTSD

Suggested Use: 

1 - 2 capsules daily

Recommended to start with lower dose for 1 - 2 weeks

Caution: 

Caution is to be used when the patient has a history of liver disease and/or hepatitis as Corydalis may increase liver enzymes in some patients

Be very cautious when prescribing together with conventional medicines, pregnancy and breastfeeding

Will have additive effect on psychotropic drugs and may cause drowsiness

5-methyltetrahydrofolate

Likely Safe:

When used orally or parenterally and appropriately. 5-methyltetrahydrofolate is safe when used in doses less than 1000 mcg per day. In cases of megaloblastic anaemia resulting from folate deficiency or malabsorption disorders such as sprue, oral doses of 1-5 mg per day can also be used safely if vitamin B12 levels are routinely measured until hematologic recovery is documented.

Warning: 

In very rare cases, Curcuma species may harm the liver. Stop use and see a doctor if you have yellowing skin/eyes or unusual: fatigue, nausea, appetite loss, abdominal pain, dark urine, or itching. If symptoms persist, talk to your health professional. Contains vitamin B6. St John’s Wort affects the way many prescription medicines work, including the oral contraceptive pill. Consult your doctor. Vitamin supplements should not replace a balanced diet. This product contains pyridoxal 5-phosphate as applicable, which may be dangerous when used in large amounts or for a long time. Stop taking this medication if you experience tingling, burning or numbness and see your healthcare practitioner as soon as possible. Phenylketonurics are warned that this product contains phenylalanine. Not permitted for use in children aged below 2 years.
Contains Phenylalanine, do not use with MAO inhibitors for depression or if any of the following conditions are present:

phenylketonuria (PKU)

hepatitis

cirrhosis

liver damage

melanoma

migraine headache

Radix Bupleuri (chai hu) should be considered contraindicated in the treatment of solid tumours, but not necessarily for haematological cancers. A research article by Shyu et al., (2004) indicated that chai hu promotes endothelial cells growth, migration and angiogenesis and therefore should be cautioned in its use. Note that this was for one fraction while other fractions may have differing effects.

Possibly Unsafe:

When used orally in large doses. Doses above 1000 mcg per day should be avoided if possible to prevent precipitation or exacerbation of neuropathy related to vitamin B12 deficiency. However, as Affect D contains significant B12 this is not a danger. There is some evidence that doses of 5 mg per day orally for up to 4 months can be used safely if vitamin B12 levels are routinely measured. Preliminary clinical research suggests daily doses of 800-1200 mcg might increase the risk of cancer and adverse cardiovascular effects if there is impaired liver function. Affect D uses the methyl form of 5-methyltetrahydrofolate and does not rely on liver metabolism. Very high doses of 15 mg per day can cause significant central nervous system (CNS) and gastrointestinal side effects.