{"product_id":"igf1-and-igf-bp3-1107","title":"IGF1 \u0026 IGF-BP3","description":"\u003cp\u003eInsulin-like growth factor 1 (IGF1) is a natural hormone the body produces. It contains seventy amino acid polypeptides that are produced by the liver and endocrine hormone system. IGF-1 also plays a role in cell repair to the muscles, brain and heart.\u003c\/p\u003e\n\u003cp\u003eInsulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults.\u003c\/p\u003e\n\u003cp\u003eIGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine\/autocrine fashion. Production is stimulated by growth hormone (GH) and can be dysfunctional due to under nutrition, growth hormone insensitivity and lack of growth hormone receptors. Approximately 98% of IGF-1 is always bound to one of 6 binding proteins (IGF-BP).\u003c\/p\u003e\n\u003cp\u003eIGFBP-3, the most abundant protein, accounts for 80% of all IGF binding. IGF-1 binds to IGFBP-3 in a 1:1 molar ratio.\u003c\/p\u003e\n\u003cp\u003eIGF-1 is a primary mediator of the effects of growth hormone (GH). Growth hormone is made in the anterior pituitary gland, released into the blood stream and then stimulates the liver to produce IGF-1. IGF-1 then stimulates systemic body growth and has growth-promoting effects on almost every cell in the body especially skeletal muscle, cartilage, bone, liver, kidney, nerves, skin and lungs.  In addition to the insulin-like effects, IGF-1 can also regulate cell growth and development especially in nerve cells as well as cellular DNA synthesis.\u003c\/p\u003e\n\u003cdiv class=\"references\"\u003e\n\u003cp\u003eReferences:Frater J, Lie D, Bartlett P, McGrath JJ. Insulin-like Growth Factor 1 (IGF-1) as a marker of cognitive decline in normal ageing: A review. \u003cem\u003eAgeing Res Rev\u003c\/em\u003e. 2018;42:14‐27. doi:10.1016\/j.arr.2017.12.002\u003c\/p\u003e\n\u003cp\u003eNicholls AR, Holt RI. Growth Hormone and Insulin-Like Growth Factor-1. \u003cem\u003eFront Horm Res\u003c\/em\u003e. 2016;47:101‐114. doi:10.1159\/000445173\u003c\/p\u003e\n\u003c\/div\u003e\u003ch3\u003eTest details\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest code:\u003c\/strong\u003e 1107\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCategory:\u003c\/strong\u003e Hormone Health\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKit requirements:\u003c\/strong\u003e SST Serum (Fasting)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollection method:\u003c\/strong\u003e CI05.15.01\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTest method:\u003c\/strong\u003e Automated chemistry (Roche Diagnostics)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTurnaround time:\u003c\/strong\u003e 7 Business Days\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eWhat is measured\u003c\/h3\u003e\u003cul class=\"analytes\"\u003e\n\u003cli\u003e\n\u003cspan\u003eIGF-BP3 (insulin-like growth factor binding protein 3)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eIGF1 (insulin-like growth factor 1)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e \u003cdiv\u003e\n\n\u003c\/div\u003e\u003ch3\u003eCommon clinical applications\u003c\/h3\u003e\u003cul class=\"common-conditions\"\u003e\n\u003cli\u003e\n\u003cimg src=\"https:\/\/nutripath.com.au\/wp-content\/uploads\/2023\/10\/Nutritional-and-Dietary-Symptoms.png\"\u003e\u003cspan\u003eNutritional and Dietary Symptoms\u003c\/span\u003e\u003cul class=\"common-conditions\"\u003e\u003cli\u003e\u003cspan\u003eChronic Fatigue\u003c\/span\u003e\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cimg src=\"https:\/\/nutripath.com.au\/wp-content\/uploads\/2023\/10\/Mental-and-Emotional-Health.png\"\u003e\u003cspan\u003eMental and Emotional Health\u003c\/span\u003e\u003cul class=\"common-conditions\"\u003e\u003cli\u003e\u003cspan\u003eDepression\u003c\/span\u003e\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cimg src=\"https:\/\/nutripath.com.au\/wp-content\/uploads\/2023\/10\/Other-Health-Conditions.png\"\u003e\u003cspan\u003eOther Health Conditions\u003c\/span\u003e\u003cul class=\"common-conditions\"\u003e\n\u003cli\u003e\u003cspan\u003eLack of stamina\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eLoss of muscle tone\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSexual dysfunction\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e \u003cdiv\u003e\n\n\u003c\/div\u003e\u003ch3\u003eResources\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/nutripath.com.au\/wp-content\/uploads\/2013\/12\/1107-IGF1-IGF-BP3-.pdf\"\u003ePatient Brochure\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/nutripath.com.au\/wp-content\/uploads\/2016\/12\/1107-GF-1-IGF-BP3.pdf\"\u003eSample Report\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cem\u003eThis test should be ordered and interpreted with guidance from a qualified healthcare practitioner.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Test information is general only. Results should be interpreted with a qualified health practitioner and do not replace medical advice or diagnosis.\u003c\/p\u003e","brand":"NutriPATH","offers":[{"title":"Default Title","offer_id":43256758272062,"sku":"NUTRIPATH-1107","price":167.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6371\/9486\/files\/logo-circleonly-450x450_7dfb4ff1-d3cb-4545-8425-ae7ffd90c5e5.png?v=1787889984","url":"https:\/\/northshorehealthclinic.com.au\/products\/igf1-and-igf-bp3-1107","provider":"NSHC","version":"1.0","type":"link"}